- This page contains the ingredients, directions and information of a certain "broad-spectrum antibiotic" that we use not only for our goats, but for our poultry as well. This information is taken directly from the product label. Please note, that the author is not a veterinarian or specialist in the medical needs for goats or poultry. This information is posted for your reference and comparison purposes only.
Liquamycin LA-200 (oxytetracycline injection) is a sterile, preconstituted solution of the broad-spectrum antiobiotic oxytetracycline (Terramycin®) by injection. Terramycin, discovered by Pfizer scientists, is an antimicrobial agent that is effective in the treatment of a wide range of diseases caused by susceptible gram-positive and gram-negative bacteria.
Liquamycin LA-200 administered to cattle or swine for the treatment of bacterial pneumonia at an intramuscular dosage of 9 mg of oxytetracycline per lb of body weight has been demonstrated in clinical trials to be as effective as 2 or 3 repeated, daily treatments of Terramycin Injectable at 3-5 mb/lb of body weight.
Liquamycin LA-200 does not require refrigeration; however, it is recommended that it be stored at room temperature, 15o - 30oC (59o-86oF). The antibiotic activity of oxytetracycline is not appreciably diminished in the precense of body fluids, serum, or exudates.
When administered to cattle, muscle discoloration may necessitate trimming the injection site(s) and surrounding tissues during the dressing procedure.
Discontinue treatment at least 28 days prior to slaughter of cattle and swine. Milk taken from animals during treatment and for 96 hours after the last treatment must not be used for food.
Exceeding the highest recommended dosage level of drug per lb of body weight per day, administering more than the recommended number of treatments, and/or exceeding 10 mL intramuscularly or subcutaneously per injection site in adult beef and dairy cattle, a 5 mL intramuscularly per injection site in adult swine, may result in antibiotic residues beyond the withdrawal period.
Reactions of an allergic or anaphylactic nature, sometimes fatal, have been known to occur in hypersensitive animals following the injection of oxytetracycline. Such adverse reactions can be characterized by signs such as restlessness, erection of hair, muscle trembling; swelling of eyelids, ears, muzzle, anus, and vulva (or scrotum and sheath in males); labored breathing, defacation and urination, glassy-eyed appearance, eruption of skin plaques, frothing from the mouth, and prostration. Pregnant animals that recover may subsequently abort. At the first sign of any adverse reaction, discontinue use of this product and administer epinephrine at the recommended dosage levels. Call a veterinarian immediately.
Shock may be observed following intravenous administration, especially where highly concentrated materials are involved. To minimize this occurrence, it is recommended that Liquamycin LA-200 be administered slowly by this route.
Shortly after injection, treated animals may have transient hemoglobinuria resulting in darkened urine.
As with all antibiotic preparations, use of this drug may result in overgrowth of nonsusceptible organisms, including fungi. A lack of response by the treated animal, or the development of new signs, may suggest that an overgrowth of nonsusceptible organisms has occurred. If any of these conditions occur, consult your veterinarian.
Store at room temperature 15o - 30oC (59o-86oF). Keep from freezing.
CARE OF SICK ANIMALS:
The use of antibiotics in the management of diseases is based on an accurate diagnosis and an adequate course of treatment. When properly used in the treatment of diseases caused by oxytetracycline-susceptible organisms, most animals that have been treated with Liquamycin LA-200 show a noticeable improvement within 24-48 hours. It is recommended that the diagnosis and treatment of animal diseases be carried out by a veterinarian. Since many diseases look alike but require different types of treatment, the use of professional veterinary and laboratory services can reduce treatment time, costs, and needless losses. Good housing, sanitation, and nutrition are important in the maintenance of healthy animals, and are essential in the treatment of diseased animals.
Liquamycin LA-200 is intended for use in the treatment of the following diseases in beef cattle; dairy cattle; calves; and swine when due to oxytetracycline-susceptible organisms;
Liquamycin LA-200 is indicated in the treatment of pneumonia and shipping fever complex associated with Pasteurella spp. and Hemphilus spp.; infectious bovine keratoconjunctivitis (pinkeye) caused by Moraxella bovis; foot rot and diphtheria caused by Fusobacterium necrophorum; bacterial enteritis (scours) caused by Escherichia coli; wooden tongue caused by Actinobacillus lignieresii; leptospirosis caused by Leptospira pomona; and wound infections and acute metritis caused by strains of staphylococci and streptococci organsims sensitive to oxytetracycline.
Liquamycin LA-200 is indicated in the treatment of bacterial enteritis (scours, colibacillosis) caused by Escherichia coli; pneumonia caused by Pasteurella multocida; and leptospirosis caused by Leptospira pomona.
In sows, Liquamycin LA-200 is indicated as an aid in the control of infectious enteritis (baby pig scours, colibacillosis) in suckling pigs caused by Escherichia coli.
Liquamycin LA-200 is to be administered by intramuscular, subcutaneous, or intravenous injection to beef cattle; dairy cattle;; and calves, including preruminating (veal) calves.
A single dosage of 9 mg of Liquamycin LA-200 per lb of body weight administered intramuscularly or subcutaneously is recommended in the treatment of the following conditions:
1) bacterial pneumonia caused by Pasteurella spp. (shipping fever) in calves and yearlings, where retreatment is impractical due to husbandry conditions, such as cattle on range, or where their repeated restraint is inadvisable;
Liquamycin LA-200 can also be administered by intravenous, subcutaneous, or intramuscular injection at a level of 3-5 mg of oxytetracycline per lb of body weight per day. In the treatment of severe foot rot and advanced cases of other indicated diseases, a dosage level of 5 mg/lb of body weight per day is recommended. Treatment should be continued 24-48 hours following remission of disease signs; however, do not exceed a total of 4 consecutive days. Consult your veterinarian if improvement is not noted within 24-48 hours of the beginning of the treatment.
2) infectious bovine keratoconjunctivitis (pinkeye) caused by Moraxella bovis.
A single dosage of 9 mg of Liquamycin LA-200 per lb of body weight administered intramuscularly is recommended in the treatment of bacterial pneumonia caused by Pasteurella multocida in swine, where retreatment is impractical due to husbandry conditions or where repeated restraint is inadvisable.
Liquamycin LA-200 can also be administered by intramuscular injection at a level of 3-5 mg of oxytetracycline per lb of body weight per day. Treatment should be continued 24-48 hours following remission of disease signs; however, not to exceed a total of 4 consecutive days. Consult your veterinarian if improvement is not noted within 24-48 hours of the beginning of treatment.
For sows, administer once intramuscularly 3 mg of oxytetracycline per lb of body weight approximately 8 hours before farrowing or immediately after completion of farrowing.
For swine weighing 25 lb of body weight and under, Liquamycin LA-200 should be administered undiluted for treatment at 9 mg/lb but should be administered diluted for treatment at 3 or 5 mg/lb.
9 mg/lb Dosage
Volume of Undiluted
3 or 5 mg/lb Dosage
Volume of Diluted
* To prepare dilutions, add 1 part Liquamycin LA-200 to 3, 5, or 7 parts of sterile water, or 5% dextrose solution as indicated; the diluted product should be used immediately.
Restricted Drug (California)
Use Only as Directed
Not For Human Use
NADA #113-232, Approved by FDA
Pfizer, Animal Health
Exton, PA 19341, USA
Div. of Pfizer Inc.
NY, NY 10017